发明名称 |
SYNTHESIS OF FUNCTIONALIZED AND UNFUNCTIONALIZED OLEFINS VIA CROSS AND RING-CLOSING METATHESIS |
摘要 |
<p>The invention is directed to the cross-metathesis and ring-closing metathesis reactions between geminal disubstituted olefins and terminal olefins, wherein the reaction employs a Ruthenium or Osmium metal carbene complex. Specifically, the invention relates to the synthesis of alpha -functionalized or unfunctionalized olefins via intermolecular cross-metathesis and intramolecular ring-closing metathesis using a ruthenium alkylidene complex. The catalysts preferably used in the invention are of general formula (I) or (II), wherein: M is ruthenium or osmium; X and X<1> are each independently an anionic ligand; L is a neutral electron donor ligand; and, R, R<1>, R<6>, R<7>, R<8>, and R<9> are each independently hydrogen or a substituent selected from the group consisting of C1-C20 alkyl, C2-C20 alkenyl, C2-C20 alkynyl, aryl, C1-C20 carboxylate, C1-C20 alkoxy, C2-C20 alkenyloxy, C2-C20 alkynyloxy, aryloxy, C2-C20 alkoxycarbonyl, C1-C20 alkylthio, C1-C20 alkylsulfonyl and C1-C20 alkylsulfinyl.</p> |
申请公布号 |
WO0200590(A1) |
申请公布日期 |
2002.01.03 |
申请号 |
WO2001US20180 |
申请日期 |
2001.06.25 |
申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY;GRUBBS, ROBERT, H.;CHATTERJEE, ARNAB, K.;MORGAN, JOHN, P.;SCHOLL, MATTHIAS;CHOI, TAE-LIM |
发明人 |
GRUBBS, ROBERT, H.;CHATTERJEE, ARNAB, K.;MORGAN, JOHN, P.;SCHOLL, MATTHIAS;CHOI, TAE-LIM |
分类号 |
B01J31/22;C07B37/00;C07B37/04;C07B61/00;C07C45/67;C07C45/69;C07C45/72;C07C49/597;C07C57/26;C07C67/293;C07C67/313;C07C67/333;C07C67/343;C07C69/145;C07C69/24;C07C69/533;C07C69/608;C07C69/618;C07C69/67;C07C69/73;C07C69/738;C07C69/767;C07C201/12;C07C205/06;C07C205/56;C07C231/12;C07C233/09;C07C233/11;C07C259/06;C07C315/04;C07C317/14;C07D203/10;C07D263/22;C07D263/24;C07D303/22;C07D309/12;C07D309/30;C07D309/32;C07D315/00;C07D317/12;C07D319/12;C07D319/14;C07D321/08;C07D413/12;C07F7/18;(IPC1-7):C07C67/02;C07F15/00;C07F9/28;C07F7/04;C07D309/18;C07D309/16;C07D263/04;C07D323/02;C07C61/35;C07D303/04 |
主分类号 |
B01J31/22 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|