发明名称 |
Production of radial glial cells |
摘要 |
The present invention relates to a method of producing radial glial cells from neural stem cells, particularly by contacting neural stem cells with epidermal growth factor (EGF), fibroblast growth factor 2 (FGF-2) and/or TGFalpha. Leukemia inhibitory factor (LIF) and ciliary neurotrophic factor (CNTF) can optionally be added to enhance the effect of EGF, FGF-1 or TGFalpha. Also provided are methods of producing radial glial cells from ependymal cells, as well as methods of proliferating ependymal cells.
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申请公布号 |
US7033995(B2) |
申请公布日期 |
2006.04.25 |
申请号 |
US20020196549 |
申请日期 |
2002.07.17 |
申请人 |
STEM CELL THERAPEUTICS INC. |
发明人 |
WEISS SAMUEL;GREGG CHRISTOPHER |
分类号 |
A61K38/18;A61K35/12;A61K35/30;A61K48/00;A61P25/00;A61P25/28;C12N5/079 |
主分类号 |
A61K38/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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