| 发明名称 |
RECOMBINANT PLASMID DNA FOR DETECTION OF AGENTS DAMAGING GENETIC APPARATUS OF CELL (VARIANTS) |
| 摘要 |
FIELD: biotechnology, molecular biology. ^ SUBSTANCE: invention proposes a recombinant plasmid DNA providing synthesis of fluorescent mutant protein GFR from Aequorea Victoria in Rec+ strains of E. coli under control of regulatory region of recA gene from Proteus mirabilis. Invention provides the enhanced sensitivity of some factors of chemical nature damaging DNA and damaging factors of physical nature also. Invention can be used food processing, pharmaceutical and chemical industry. ^ EFFECT: valuable biological properties of plasmid DNA. ^ 2 cl, 12 dwg, 2 ex |
| 申请公布号 |
RU2311459(C2) |
申请公布日期 |
2007.11.27 |
| 申请号 |
RU20050135233 |
申请日期 |
2005.11.14 |
| 申请人 |
GOSUDARSTVENNOE UCHREZHDENIE NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT BIOKHIMII SIBIRSKOGO OTDELENIJA ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK (GU NII BIOKHIMII SO RAMN) |
发明人 |
RJABCHENKO ALEKSANDR VLADIMIROVICH;LAVRINENKO IGOR' ALEKSEEVICH;BEKLEMISHEV ANATOLIJ BORISOVICH |
| 分类号 |
C12N15/72;C12N15/12 |
主分类号 |
C12N15/72 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
