Error models for location analysis data that robustly handles replicate data

摘要

A computer programmed to determine a standard error of a log ratio measurement of an immunoprecipitated sample and a whole cell extract at a particular feature is disclosed herein. A first quantity standing in known relation to the standard error of a signal intensity measurement corresponding to the immunoprecipitated sample at the particular feature is found. Also, a second quantity standing in known relation to the standard error of a signal intensity measurement corresponding to the whole cell extract at the particular feature is found. The standard error of the log ratio measurement of the immunoprecipitated sample and the whole cell extract sample is determined based upon said first and second quantities.