发明名称 Intermediates for 2-piperidino-1-alkanols
摘要 2-(8-Azabicyclo[3.2.1]oct-8-yl)alkanols of the formula <IMAGE> (I) wherein Q is S or CH=CH; X is H, OH or another aromatic substituent; R is hydrogen, alkyl, alkenyl or alkynyl; Y and Y1 are taken together and are arylmethylene or aralkylmethylene (or a corresponding epoxy derivative) or Y and Y1 are taken separately and Y is hydrogen or OH, and Y1 is aryl, aralkyl, arylthio, or aryloxy; and structurally related 2-(piperidino)alkanols; pharmaceutical compositions thereof; methods of treating CNS disorders therewith; and intermediates useful in the preparation of said compounds.
申请公布号 US5391742(A) 申请公布日期 1995.02.21
申请号 US19940228466 申请日期 1994.04.15
申请人 PFIZER INC. 发明人 CHENARD, BERTRAND L.
分类号 C07D491/107;A61K31/33;A61K31/40;A61K31/435;A61K31/46;A61K31/695;A61P25/00;A61P25/28;C07D;C07D207/08;C07D207/12;C07D207/20;C07D209/02;C07D211/14;C07D211/44;C07D211/48;C07D211/52;C07D211/54;C07D211/70;C07D211/74;C07D405/04;C07D407/04;C07D407/14;C07D409/06;C07D409/14;C07D411/14;C07D451/02;C07D451/04;C07D451/06;C07D491/10;C07D491/20;C07F7/08;C07F7/18;(IPC1-7):C07D451/06 主分类号 C07D491/107
代理机构 代理人
主权项
地址