发明名称 |
INHIBITORS OF CRYSTALLIZATION IN A SOLID DISPERSION |
摘要 |
<p>A pharmaceutical composition is disclosed which comprises a solid dispersion of a pharmaceutical compound in a water soluble carrier, such as polyethylene glycol (PEG), and a crystallization inhibitor, such as polyvinylpyrrolidone or hydroxypropylmethylcellulose. The solid dispersion may optionally be encapsulated in hard gelatin capsules, compressed into a tablet, or may be granulated wiht a pharmaceutically acceptable granulating agent. Also disclosed are methods of making said solid dispersion and methods of treatment employing said solid dispersion.</p> |
申请公布号 |
WO0134119(A3) |
申请公布日期 |
2001.11.22 |
申请号 |
WO2000US31072 |
申请日期 |
2000.11.10 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
KRILL, STEVEN, K.;FORT, JAMES, J.;LAW, DEVALINA;SCHMITT, ERIC, A.;QIU, YIHONG |
分类号 |
A61K47/32;A61K9/16;A61K9/20;A61K9/48;A61K31/216;A61K31/343;A61K31/427;A61K31/513;A61K45/00;A61K47/34;A61K47/38;A61P3/06;A61P31/10;A61P43/00;(IPC1-7):A61K9/14;A61P31/18 |
主分类号 |
A61K47/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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