COMPOSITION COMPRISING THE EXTRACT OF ARALIA CORDATA THUNB FOR THE PREVENTION OR TREATMENT OF INFLAMMATION AND ALLERGIC DISEASE

摘要

A composition for the prevention or treatment of inflammation and allergic disease comprising the extract of Aralia cordata Thunb is provided to reduce side effects of the prevention or treatment, and to inhibit 5-lipoxygenase dependent production of leukotriene C4 which participates in allergy and inflammation responses. The composition for the prevention or treatment of inflammation and allergic disease comprises the extract of Aralia cordata Thunb as an effective ingredient, wherein the Aralia cordata Thunb extract is obtained by extracting Aralia cordata Thunb with a solvent selected from water, methanol and ethanol; the composition treats an animal model having inflammation induced by croton oil and phorbol myristate acetate; the amount of Aralia cordata Thunb extract is 0.01-50% based on the total weight of the composition; and the inflammation and allergic diseases are acute or chronic inflammation disease, bronchial asthma, allergic rhinitis, allergic asthma or allergic dermatitis.