DIFFERENTIAL DIAGNOSTICS AND THERAPY OF VIRALLY INDUCED HEART MUSCLE DISEASE

摘要

Novel polynucleotide sequences and amino acid sequences of parvovirus B19, methods for differential diagnosis of viral infection in myocardial disease and pharmaceutical compositions for the treatment thereof are disclosed. A method for the detection of a viral infection of a patient comprises the detection in a blood vessel or heart muscle tissue sample, outside of the human body, the presence or absence of Parvovirus B19 genotype 1 or Parvovirus B19 genotype 2 or Human Herpesvirus 6 or both. Similarly provided is the use of Interferon alpha in the preparation of a pharmaceutical composition for the prevention or treatment of myocardial infection by Parvovirus B19 or Human Herpesvirus 6, optionally with the addition of ribavirin.