发明名称 |
Methods and compositions for alleviating pain |
摘要 |
The present invention provides a method for the long-term relief of chronic pain in a subject by activating in the subject an analgesic alpha-adrenergic receptor in the absence of alpha-2A receptor activation over a period of at least three days, such that relief of chronic pain is maintained in the absence of continued activation of said receptor. The analgesic alpha-adrenergic receptor can be, for example, the alpha-2B receptor.
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申请公布号 |
US7345065(B2) |
申请公布日期 |
2008.03.18 |
申请号 |
US20020153154 |
申请日期 |
2002.05.21 |
申请人 |
ALLERGAN, INC. |
发明人 |
GIL DANIEL W.;DONELLO JOHN E. |
分类号 |
A61K31/425;G01N33/50;A61K31/137;A61K31/17;A61K31/4164;A61K31/4166;A61K31/4168;A61K31/4174;A61K31/4178;A61K31/421;A61K31/426;A61K31/433;A61K31/498;A61K31/538;A61K45/06;A61P1/04;A61P3/10;A61P19/02;A61P25/02;A61P25/04;A61P25/06;A61P29/00;A61P29/02;A61P35/00;G01N33/15 |
主分类号 |
A61K31/425 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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