发明名称 IMIDAZOLE DERIVATIVES AS PHOSPHODIESTERASE VII INHIBITORS
摘要 The invention relates to imidazole derivatives of formula (I), wherein R1 means H, A, benzyl, indane-5-yl, 1,2,3,4-tetrahydro-naphthaline-5-yl, dibenzothiophene-2-yl or phenyl that is unsubstituted or substituted once, twice or three times by means of Hal, A, A- CO-NH, benzyloxy, alkoxy, COOH or COOA, R2 means H or A, X means O or S, Hal means F, Cl, Br or I and A means alkyl with 1 to 6 C-atoms. The invention also relates to the physiologically acceptable salts and/or solvates thereof acting as phosphodiesterase VII inhibitors. The invention further relates to the use thereof for producing a medicament.
申请公布号 CA2388314(C) 申请公布日期 2009.06.16
申请号 CA20002388314 申请日期 2000.10.10
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG 发明人 WOLF, MICHAEL;ROCHUS, JONAS;GASSEN, MICHAEL;POSCHKE, OLIVER;EGGENWEILER, MICHAEL
分类号 C07D495/04;A61K31/4188;A61P1/04;A61P3/10;A61P7/00;A61P9/10;A61P11/00;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P19/10;A61P25/00;A61P25/28;A61P29/00;A61P31/04;A61P35/00;A61P37/00;A61P37/04;A61P37/06;A61P43/00;C07D235/00;C07D311/00;C07D335/00;C07D491/04;C07D491/052 主分类号 C07D495/04
代理机构 代理人
主权项
地址