Alternating sympathomimetic therapy for the treatment of respiratory ailments

摘要

A combination of dosage units for alleviating respiratory ailments and a method of alleviating respiratory ailments which uses this combination of dosage units. The dosage units comprise one or more first dosage units comprising pseudoephedrine and/or a pharmaceutically acceptable salt thereof and one or more second dosage units comprising phenylephrine and/or a pharmaceutically acceptable salt thereof.

主权项

1. A regimen for the alleviation of a condition which comprises nasal congestion, wherein the regimen comprises administering to a subject in need thereof one or more first dosage units which comprise at least one of pseudoephedrine and a pharmaceutically acceptable salt thereof in an amount which is sufficient to maintain a therapeutically effective plasma level of pseudoephedrine for a first period, and subsequently administering to the subject one or more second dosage units which are different from the first dosage units and comprise at least one of phenylephrine and a pharmaceutically acceptable salt thereof in an amount which is sufficient to maintain a therapeutically effective plasma level of phenylephrine for a second period, the first and second dosage units being administered such that there is substantially no gap between the first and second periods.