发明名称 Process for producing 1-benzyl-4-[ (5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine or hydrochloride thereof
摘要 1-Benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine or hydrochloride thereof, which is useful as a drug, can be produced in high purity by safer and easier operations suitable for industrial production by subjecting 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-ylidene]methyl-piperidine or a solvate thereof to catalytic hydrogenation in the presence of a palladium-alumina catalyst and if necessary, converting the thus obtained compound to its hydrochloride.
申请公布号 US2007088055(A1) 申请公布日期 2007.04.19
申请号 US20060546444 申请日期 2006.10.12
申请人 EISAI R&D MANAGEMENT CO., LTD. 发明人 IMAI AKIO
分类号 C07D211/06;A61K31/445 主分类号 C07D211/06
代理机构 代理人
主权项
地址