COMPOUNDS AND METHODS FOR THE MODULATION OF TOLL-LIKE RECEPTOR FUNCTION
摘要
The present invention relates to compositions and methods for use in the treatment of conditions such as septicaemia and septic shock. The invention further provides compositions and methods for the suppression Toll-like Receptor 4 mediated activation of the immune system. The invention further provides screening assays to identify compounds which have utility in the foregoing compositions and methods.
申请公布号
WO2008046902(A3)
申请公布日期
2008.09.12
申请号
WO2007EP61182
申请日期
2007.10.18
申请人
THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN;O'NEILL, LUKE ANTHONY;CARPENTER, SUSAN;DUNNE, AISLING
发明人
O'NEILL, LUKE ANTHONY;CARPENTER, SUSAN;DUNNE, AISLING