SPEKTRAL BILLEDDANNELSE TIL MÅLING AF NUKLEÆRE PATOLOGISKE TRÆK I CANCERCELLER FREMSTILLET TIL IN SITU ANALYSE
摘要
In general, the presently disclosed technology relates to identification of cancer subtypes. More specifically, the technology relates to methods for determining molecular drivers of cancer and/or progression using a multivariate image data and statistical analysis of in-situ molecular markers and morphological characteristics in the same cells of a biological sample suspected of cancer. This analysis takes place after a single acquisition that obtains the molecular and anatomic morphology data in parallel. The analysis compares specific morphological and molecular markers to known samples exhibiting particular genetic drivers of the cancer. This method provides statistical information that allows for an increased confidence in the identification of specific molecular drivers of the cancer.
申请公布号
DK2707505(T3)
申请公布日期
2016.07.25
申请号
DK20120725639T
申请日期
2012.05.07
申请人
Ventana Medical Systems, Inc.;Cornell University
发明人
DEMICHELIS, Francesca;GARSHA, Karl;MILLER, Phillip C;NAGLE, Ray B;OTTER, Michael;RUBIN, Mark A.;PESTANO, Gary Anthony