Pharmaceutical composition comprising bicyclic pyridinol derivatives for preventing or treating diseases caused by angiogenesis

摘要

Disclosed is a pharmaceutical composition including a bicyclic pyridinol derivative as an active ingredient for preventing or treating diseases caused by angiogenesis. The bicyclic pyridinol derivative expressed by Chemical Formula 1 can be effectively used as a drug for preventing and treating diseases caused by angiogenesis since it inhibits neovascularization in a chorioallantoic membrane model.

主权项

1. A method of inhibiting angiogenesis which supports growth and metastasis of a lung cancer, comprising:
administering to a subject a pharmaceutical composition comprising a therapeutically effective amount of bicyclic pyridinol derivative expressed by the following Chemical Formula: wherein the angiogenesis supporting the growth and metastasis of the lung cancer is inhibited in the subject.