发明名称 Auto magnetic metal salen complex compound
摘要 A drug using the magnetic properties of a metal salen complex as represented by the following general formula in order to magnetize the intended drug by chemically binding the drug to a metal salen complex so that the drug can be delivered to the target diseased site. The drug can be delivered to the diseased site using the magnetic properties of the drug per se without using a carrier made of a magnetic substance as in the conventional methods.;
申请公布号 US9505732(B2) 申请公布日期 2016.11.29
申请号 US201113112409 申请日期 2011.05.20
申请人 IHI CORPORATION 发明人 Ishikawa Yoshihiro;Eguchi Haruki
分类号 C07F5/00;C07D305/14;A61K31/135;A61K31/167;A61K31/295;A61K31/337;C07C251/24 主分类号 C07F5/00
代理机构 代理人
主权项 1. An auto magnetism-imparting metal salen complex molecule represented by formula (IV): wherein M is selected from Fe, Cr, Mn, Co, Ni, Mo, Ru, Rh, Pd, W, Re, Os, Ir, Pt, Nd, Sm, Eu and Gd, and wherein medicinal molecules are bonded via an amide group to locations 5 and 10 or locations 2 and 13, and the medicinal molecules are independently selected from: paclitaxel,gemfibrozil,wherein Ac is an acetyl group and Bz is a benzoyl group,
地址 Tokyo JP