发明名称 |
Serine protease variants having amino acid deletions and substitutions |
摘要 |
The present invention relates to variants of serine proteases having decreased immunogenicity relative to their corresponding wild-type proteases. More particularly, the present invention relates to variants having a modified amino acid sequence of a wild-type amino acid sequence, wherein the modified amino acid sequence comprises a deletion and, optionally, a substitution of one or more specifically identified positions corresponding to subtilisin BPN'. The invention further relates to mutant genes encoding such variants and cleaning and personal care compositions comprising such variants. |
申请公布号 |
AU2742699(A) |
申请公布日期 |
1999.10.18 |
申请号 |
AU19990027426 |
申请日期 |
1999.03.25 |
申请人 |
THE PROCTER & GAMBLE COMPANY |
发明人 |
DONN NELTON RUBINGH;ELIZABETH ELLEN SIKORSKI;PAUL ELLIOTT CORREA |
分类号 |
C12N15/09;A61K8/00;A61K8/02;A61K8/66;A61K8/96;A61Q5/00;A61Q5/02;A61Q11/00;A61Q19/00;A61Q19/10;C12N9/54;C12N15/57 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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