IMPLANTABLE DRUG DELIVERY DEVICES FOR GENITOURINARY SITES

摘要

Implantable drug delivery devices are provided to have a deployment shape for implantation in the body and a retention shape for retention in the body. The device may have one or more elongated drug reservoirs containing a drug, and the drug reservoir may be formed from a deformable material. In one case, a first filament is attached to the first end of the drug reservoir and second filament is attached to the second end of the drug reservoir, wherein a fastener is positioned about the first and second filaments to permit shortening and prevent lengthening of the filaments with reference to the ends of the drug reservoir, as a means for transforming the device from the implantation shape to the retention shape.

主权项

1. An implantable drug delivery device comprising:
a shape-memory filament that is preprogrammed to achieve an expanded shape and is deformable into an elongated shape; and a plurality of extended-release drug beads, each of which comprises a drug, spaced along the filament.