| 发明名称 | 3-O-acyl-ingenol analogues | ||
| 摘要 | The present invention relates to a compound according to formula I;wherein R1 represents hydrogen, R2 represents hydroxyl and R3 represents hydroxyl;or R1 represents methyl, R2 represents hydroxyl and R3 represents hydrogen;or R1 represents methyl, R2 represents hydrogen and R3 represents hydroxyl;or R1 represents methyl, R2 represents hydrogen and R3 represents hydrogen;or pharmaceutically acceptable hydrates or solvates thereof. The invention further relates to said compounds for use as a medicament, to pharmaceutical compositions comprising said compounds, to methods of treating diseases with said compounds and to intermediates for the preparation of said compounds. | ||
| 申请公布号 | US9409931(B1) | 申请公布日期 | 2016.08.09 |
| 申请号 | US201514739731 | 申请日期 | 2015.06.15 |
| 申请人 | LEO LABORATORIES LIMITED | 发明人 | Baran Phillippe S.;Felding Jakob;Jin Yehua;Yeh Chien-Hung |
| 分类号 | C07C69/75;A61K31/215;A61K31/695;C07F7/08 | 主分类号 | C07C69/75 |
| 代理机构 | Birch, Stewart, Kolasch & Birch, LLP | 代理人 | Birch, Stewart, Kolasch & Birch, LLP |
| 主权项 | 1. A compound according to formula I wherein R1 represents hydrogen, R2 represents hydroxyl and R3 represents hydroxyl; or R1 represents methyl, R2 represents hydroxyl and R3 represents hydrogen; or R1 represents methyl, R2 represents hydrogen and R3 represents hydroxyl; or R1 represents methyl, R2 represents hydrogen and R3 represents hydrogen; or hydrates or solvates thereof. | ||
| 地址 | Dublin IE | ||