发明名称 CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE-Y1 SPECIFIC LIGANDS
摘要 This invention encompasses compounds of formula (I) and the pharmaceutically acceptable salts thereof, wherein X1, X2, X3 represent organic or inorganic susbtituents, n is 1, 2, or 3, R1-R4 are hydrogen or organic substituents, and B is nitrogen, carbon, sulfur or oxygen, useful in the diagnosis and treatment of feeding disorders such as obesity and bulimia and cardiovascular diseases such as essential hypertension and congestive heart failure due to the binding of these compounds to human Neuropeptide Y1 receptors.
申请公布号 CA2260982(A1) 申请公布日期 1998.01.29
申请号 CA19972260982 申请日期 1997.07.18
申请人 NEUROGEN CORPORATION 发明人 PETERSON, JOHN M.;BLUM, CHARLES A.;HUTCHISON, ALAN
分类号 C07D295/12;A61K31/495;A61K31/496;A61K31/5375;A61P3/00;A61P9/04;A61P9/12;A61P43/00;C07D211/46;C07D211/58;C07D211/74;C07D295/135;C07D295/14;C07D295/155;C07D295/20;C07D491/10;C07D491/113;(IPC1-7):C07D295/205;C07D241/04;C07D401/12;C07D403/12;C07D409/12;C07D333/36;C07D239/42;A61K31/535;A61K31/54;C07D211/72;C07D213/74 主分类号 C07D295/12
代理机构 代理人
主权项
地址