A fuel cell stack has fuel cell units. Each of the fuel cell units includes first and second membrane electrode assemblies and first to third separators sandwiching the first and second membrane electrode assemblies. A positioning mechanism is used for positioning the first to third separators in alignment with each other. The positioning mechanism includes a first protruded portion and a second protruded portion. The first protruded portion protrudes from one surface of the second separator for positioning the first separator. The second protruded portion protrudes from the other surface of the second separator for positioning the third separator.