发明名称 |
METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION. |
摘要 |
A method of preparing Compound (1) or a pharmaceutically acceptable salt thereof: comprises: (a) reacting Compound (X): a pharmaceutically acceptable salt thereof with Compound (Y): in the presence of a palladium catalyst and a carbonate or phosphate base to form compound (Z): or a pharmaceutically acceptable salt thereof; and (b) deprotecting the Ts group of Compound (Z) to form Compound (1) or a pharmaceutically acceptable salt thereof. |
申请公布号 |
MX2016006200(A) |
申请公布日期 |
2016.08.08 |
申请号 |
MX20160006200 |
申请日期 |
2014.11.12 |
申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
Gerald J. TANOURY;Peter Jamison ROSE;William Aloysius NUGENT;Vadims DVORNIKOVS |
分类号 |
C07D471/04;C07C51/083 |
主分类号 |
C07D471/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|