| 发明名称 |
ANTIBODIES AGAINST CD38 FOR TREATMENT OF MULTIPLE MYELOMA |
| 摘要 |
PROBLEM TO BE SOLVED: To provide antibody medicines useful for the treatment of multiple myeloma.SOLUTION: The present invention provides isolated human monoclonal antibodies which bind to CD38 antibodies expressed in large quantities on the surface of a human blood cell, particularly a malignant phenotype cell such as multiple myeloma, and related antibody-based compositions and molecules. Also disclosed are pharmaceutical compositions comprising the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.SELECTED DRAWING: None |
| 申请公布号 |
JP2016169226(A) |
申请公布日期 |
2016.09.23 |
| 申请号 |
JP20160114979 |
申请日期 |
2016.06.09 |
| 申请人 |
GENMAB AS |
发明人 |
WEERS MICHEL DE;GRAUS YVO;OPRINS JUDITH;PARREN PAUL PARREN;WINKEL JAN VAN DE;VUGT MARTINE VAN |
| 分类号 |
C07K16/28;A01H1/00;A01K67/027;A61K31/7088;A61K38/00;A61K45/00;A61K49/00;A61P1/18;A61P11/00;A61P13/08;A61P15/08;A61P19/02;A61P27/16;A61P29/00;A61P35/00;A61P35/02;C07K14/00;C07K16/18;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N5/12;C12N15/00;C12N15/02;C12N15/09;C12Q1/02;C12Q1/04;G01N33/53 |
主分类号 |
C07K16/28 |
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