| 发明名称 |
METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS |
| 摘要 |
The present invention relates to methods and intermediates useful for the synthesis of protein deacetylase inhibitors. |
| 申请公布号 |
US2016355486(A1) |
申请公布日期 |
2016.12.08 |
| 申请号 |
US201615176826 |
申请日期 |
2016.06.08 |
| 申请人 |
Acetylon Pharmaceuticals, Inc. |
发明人 |
Seyedi Farzaneh;van Duzer John H. |
| 分类号 |
C07D239/42 |
主分类号 |
C07D239/42 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of making compound (Ia): comprising the steps of: converting compound 11a into compound 3a: wherein X is selected from fluorine, chlorine, bromine and iodine;Z is selected from the group consisting of —CN and —CO2R; andR is C1-C6 alkyl; and converting compound 3a into compound (Ia). |
| 地址 |
Boston MA US |
