发明名称 ION INTRODUCING METHOD AND COMPOSITION FOR ENHANCING SKIN CONCENTRATION OF ACTIVATOR
摘要 PURPOSE: To improve an administration velocity by increasing a dermal concentration of an ionically introduced active substance percutaneously administered by an ion-introducing method. CONSTITUTION: A composition capable of being used as a medicinal agent used as an ion-introducing administration and having effects for increasing dermal concentration of the active agent by adding (B) a vasoconstrictor in an amount for increasing the concentration in the skin, preferablyα-adrenaline- acting agent or imidazoline, preferably naphazoline, oxametazoline, tetrahydrozaline, phenoxanoline, indanazoline, tramazoline, tymazoline or xylometazoline, especially naphazoline or exametazoline to (A) an ion- introducing active agent preferably selected from curing agents, anesthetics, hormones and proteins.
申请公布号 JPH0597709(A) 申请公布日期 1993.04.20
申请号 JP19910051736 申请日期 1991.03.15
申请人 BECTON DICKINSON & CO 发明人 BAATON EICHI SEIJI JIYUNIAA;JIEEMUZU II RIBIIRU
分类号 A61K9/70;A61K31/165;A61K31/415;A61K31/445;A61K38/00;A61K38/22;A61K45/06;A61K45/08;A61K47/22;A61N1/30;A61P9/00;A61P23/02;A61P25/02;A61P43/00 主分类号 A61K9/70
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