发明名称 |
Retroviral vectors pseudotyped with srv-3 envelope glycoprotein sequences |
摘要 |
Cells producing recombinant retroviral particles are provided. The cells contain a first vector having a coding region encoding retroviral LTRs and a packaging signal under the control of an expression control system, a tRNA binding site located upstream from the packaging signal and origin of second strand DNA synthesis located downstream from the packaging signal. The cells also contain a second vector having a coding region encoding retroviral capsid proteins gag and pol under the control of an expression control system and a third vector having a coding region encoding a simian type D retrovirus envelope glycoprotein under the control of an expression control system. |
申请公布号 |
AU7470096(A) |
申请公布日期 |
1997.04.28 |
申请号 |
AU19960074700 |
申请日期 |
1996.10.04 |
申请人 |
CHIRON CORPORATION |
发明人 |
MOHAMMAD AYUB KHAN;ROBERT O RALSTON;JOHN E. MURPHY |
分类号 |
C12N15/09;C07K14/15;C12N5/10;C12N7/00;C12N15/867 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|