| 发明名称 |
TRICYCLIC DERIVATIVES AND THEIR USE IN PHARMACEUTICALS |
| 摘要 |
<p>Disclosed are compounds of Formula I: <IMAGE> (I) or a pharmaceutically acceptable salt or solvate thereof, wherein: R4 is alkenyl, alkoxy, or -OH. Also disclosed are pharmaceutical compositions containing compounds of Formula I, methods for inhibiting tumor necrosis factor- alpha , and methods for treating septic shock, inflammation, or allergic disease.</p> |
| 申请公布号 |
GR3030036(T3) |
申请公布日期 |
1999.07.30 |
| 申请号 |
GR19990401113T |
申请日期 |
1999.04.23 |
| 申请人 |
SCHERING CORPORATION |
发明人 |
TING, PAULINE, C.;FRIARY, RICHARD, J.;TOM, WING, C.;LEE, JOE, F.;SEIDL, VERA, A. |
| 分类号 |
C07D211/14;A61K31/135;A61K31/165;A61K31/335;A61K31/445;A61K31/451;A61P29/00;A61P37/08;C07C211/31;C07C211/32;C07C215/20;C07C215/38;C07C217/16;C07C217/48;C07C233/05;C07C233/13;C07C235/34;C07D211/70;C07D313/12;(IPC1-7):C07D313/12;A61K31/13 |
主分类号 |
C07D211/14 |
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