发明名称 |
HLA-G isoform for use in the treatment of a disease associated with bone resorption |
摘要 |
Novel use of HLA-G isoforms in the treatment or prevention of diseases in which bone resorption is observed. |
申请公布号 |
US9375464(B2) |
申请公布日期 |
2016.06.28 |
申请号 |
US201113989303 |
申请日期 |
2011.11.23 |
申请人 |
Etablissement Francais du Sang;Commissariat a l'Energie Atomique et aux Energies Alternatives |
发明人 |
Deschaseaux Frédéric;Sensebe Luc;Rouas-Freiss Nathalie |
分类号 |
A61K38/17;A61P19/08;A61K39/00 |
主分类号 |
A61K38/17 |
代理机构 |
Morgan, Lewis & Bockius LLP |
代理人 |
Morgan, Lewis & Bockius LLP |
主权项 |
1. A method of treating bone resorption in a subject suffering from excess bone resorption, comprising administering to the subject a pharmaceutical composition comprising an isolated isoform of HLA-G selected from the group consisting of HLA-G1 and HLA-G5 and at least one pharmaceutically acceptable vehicle, wherein the isoform of HLA-G is in monomeric form. |
地址 |
Saint Denis FR |