发明名称 HLA-G isoform for use in the treatment of a disease associated with bone resorption
摘要 Novel use of HLA-G isoforms in the treatment or prevention of diseases in which bone resorption is observed.
申请公布号 US9375464(B2) 申请公布日期 2016.06.28
申请号 US201113989303 申请日期 2011.11.23
申请人 Etablissement Francais du Sang;Commissariat a l'Energie Atomique et aux Energies Alternatives 发明人 Deschaseaux Frédéric;Sensebe Luc;Rouas-Freiss Nathalie
分类号 A61K38/17;A61P19/08;A61K39/00 主分类号 A61K38/17
代理机构 Morgan, Lewis & Bockius LLP 代理人 Morgan, Lewis & Bockius LLP
主权项 1. A method of treating bone resorption in a subject suffering from excess bone resorption, comprising administering to the subject a pharmaceutical composition comprising an isolated isoform of HLA-G selected from the group consisting of HLA-G1 and HLA-G5 and at least one pharmaceutically acceptable vehicle, wherein the isoform of HLA-G is in monomeric form.
地址 Saint Denis FR