CATECHOL-RICH POLYMERS FROM N-SUBSTITUTED MALEIMIDES

摘要

Disclosed are monomers, polymers and a method of making polymers that retain the ability of the polymer to from reversible and irreversible bonds. Gels comprising the polymers have the ability to coordinate metal ions and bind biopolymers.

主权项

1. A compound represented by Formula I: wherein, independently for each occurrence:
Z is hydrogen or optionally substituted alkyl, acyl, acyloxy, aryl, sulfonate, sulfone, sulfoxide, or sulfonamide;L is —(C(R1)2)n—, or —(C(R1)2)nO—;R is selected from the group consisting of hydrogen, hydroxyl, halogen, nitro, cyano, alkyl, alkenyl, acyl, aryl, alkylamino, acylamino, alkoxy, acyloxy, hydroxyalkyl, alkoxyalkyl, aminoalkyl, (alkylamino)alkyl, alkylthio, thioalkyl, (alkylthio)alkyl, alkynyl, carboxyl, sulfate, amino, ether, thioether, ester, amide, thioester, carbonate, carbamate, urea, sulfonate, sulfone, sulfoxide, sulfonamide, heteroaryl, carbocyclyl, heterocyclyl, aralkyl, arylalkoxy, heteroaralkyl, carbocyclylalkyl, heterocyclylalkyl, and —OR2; provided that two instances of R represent —OR2;R1 is hydrogen or alkyl;R2 is hydrogen or optionally substituted alkyl, acyl, or aryl; andn is 1, 2, 3, 4, 5, or 6.