发明名称 |
Antibodies that bind to OX40 and their uses |
摘要 |
Abstract The present invention relates to antagonist antibodies or fragments thereof that bind to human OX40. More specifically, the present invention relates to an antagonist antibody or fragment 5 thereof that binds to human OX40 comprising a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO: 1, and/or a heavy chain CDR2 comprising the amino acid sequence of SEQ ID NO: 2, and/or a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO: 3; and/or comprising a light chain CDRl comprising the amino acid sequence of SEQ ID NO: 4, and/or a light chain CDR2 comprising the amino acid sequence of SEQ ID 10 NO: 5 and/or a light chain CDR3 comprising the amino acid sequence of SEQ ID NO: 6. |
申请公布号 |
AU2016204274(A1) |
申请公布日期 |
2016.07.14 |
申请号 |
AU20160204274 |
申请日期 |
2016.06.23 |
申请人 |
GLENMARK PHARMACEUTICALS S.A. |
发明人 |
ATTINGER, ANTOINE;BLEIN, STANISLAS;BACK, JONATHAN ALBERT;LISSILAA, RAMI;HOU, SAMUEL |
分类号 |
A61P37/06;A61K39/395;C07K16/28 |
主分类号 |
A61P37/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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