Optical device for performing an assay

摘要

There is provided a device, such as a microfluidic device, for performing an assay including: a substrate comprising a channel, such as a microfluidic channel; at least one optical element having an input port arranged to be optically coupled to a light source; an output port optically coupled to at least a portion of the channel; and a light guide portion optically connecting the input port and output port; and a detection port optically coupled to said at least a portion of the channel. The device provides an improved geometry which addresses problems related to traditional orthogonal detection arrangements and in-line detection systems.

主权项

1. A device for performing an assay comprising:
a substrate comprising a channel; at least one optical element, each of the at least one optical elements comprising:
an input port having an optical axis substantially perpendicular to the substrate;an output port optically coupled to at least a portion of the channel, the output port having an optical axis substantially parallel to the substrate; anda light guide portion optically connecting the input port and the output port, the light guide portion being configured to transmit incident light inputted at the input port in a direction along the optical axis of the input port to the output port such that the incident light is outputted from the output port and illuminates said least a portion of the channel in a direction along the optical axis of the output port; and for each of the at least one optical elements, a detection port spatially offset from the input port of the optical element associated with the detection port and optically coupled to said at least a portion of the channel, the detection port being configured to receive light emitted from the channel along an optical axis substantially parallel to the optical axis of the input port of the optical element associated with the detection port.