FORMULATIONS OF HYDROPHILIC COMPOUNDS

摘要

A formulation includes a continuous hydrophobic phase, a hydrophilic phase, at least one hydrophilic compound substantially dissolved in the hydrophilic phase, and a stabilizing component. The stabilizing component can contain D-a-tocopheryl polyethylene glycol 1000 succinate (TPGS) and/or at least one emulsifier having a hydrophilic-lipophilic balance (HLB) value of at least 10. In one alternative, the stabilizing component contains a first, polysorbate emulsifier having an HLB value of at least 10, and a second emulsifier having an HLB value of less than 10.