主权项 |
1. A method of treating a cognitive impairment in a patient in need thereof, comprising administering to the patient a compound represented by formula (I) in which R1 is 1-azabicyclo[2.2.2]oct-3-yl optionally substituted by (C1-C6)-alkyl, A is methylene or ethylene, R2 is benzothiophenyl optionally substituted by radicals selected from the group of halogen, formyl, —CO—NR4R5, —CO—OR6, —NR7R8, —NR9—CO—R10, cyano, trifluoromethyl, trifluoromethoxy, nitro, optionally hydroxyl-, amino-, —NH—CO—R11— or cyano-substituted (C1-C6)-alkyl, (C1-C6)-alkoxy, (C1-C6)-alkylthio,
in which R4, R5, R6, R7, R8, R9, R10 and R11 are independently of one another hydrogen, (C1-C6)-alkyl, phenyl or benzyl,and R3 is hydrogen or (C1-C6)-alkyl, or a salt thereof. |