发明名称 HETEROCYCLIC COMPOUND
摘要 The problem of the present invention is to provide a compound having a PDE2A inhibitory action, and useful as a prophylactic or therapeutic drug for schizophrenia, Alzheimer's disease and the like. The present invention relates to a compound represented by the formula (I):;;wherein each symbol is as described in the DESCRIPTION, or a salt thereof.
申请公布号 US2016264536(A1) 申请公布日期 2016.09.15
申请号 US201415031505 申请日期 2014.10.22
申请人 Takeda Pharmaceutical Company Limited 发明人 SETO Masaki;BANNO Yoshihiro;IMAEDA Toshihiro;KAJITA Yuichi;ASHIZAWA Tomoko;KAWASAKI Masanori;NAKAMURA Shinji;MIKAMI Satoshi;NOMURA Izumi;TANIGUCHI Takahiko;MARUI Shogo
分类号 C07D277/56;C07D403/12;C07D239/28;C07D403/04;C07D239/47;C07D239/36;C07D239/52;C07D241/24;C07D498/08;C07D413/04;C07D405/04;C07D401/04;C07D417/04;C07D409/04;C07D401/12;C07D239/42 主分类号 C07D277/56
代理机构 代理人
主权项 1. A compound represented by the formula (I): wherein ring A is an optionally further substituted 5- or 6-membered nitrogen-containing heterocycle, as a ring A-constituting atom is ═N— or —N═, ring B is a benzene ring or a pyridine ring, each of which is optionally further substituted, X is a carbon atom or a nitrogen atom, L is a bond or an optionally substituted C1-2 alkylene group, Y is (1) the formula —CH2—O—R1 wherein R1 is a substituent, or (2) the formula: wherein R2 and R3 are each independently a hydrogen atom or a substituent, R4 is a substituent, or R3 and R4 are joined to optionally form, together with the adjacent carbon atom, an optionally further substituted ring, provided when L is a bond, then R3 and R4 are not 3-pyridyl groups at the same time, and Z is a substituent, (provided that 3-amino-N-[1-(4-chlorophenyl)-3-methoxypropyl]pyrazine-2-carboxamide is excluded), or a salt thereof.
地址 Osaka-shi, Osaka JP