发明名称 |
Adenovirus comprising an albumin-binding moiety |
摘要 |
The invention relates to a recombinant adenovirus comprising an albumin-binding moiety on the outer surface of the adenoviral hexon protein, pharmaceutical compositions containing it and its medical use. Particularly, the invention relates to an oncolytic adenovirus comprising a sequence encoding an albumin-binding moiety inserted in the hypervariable region 1 (HVRl) of the hexon protein coding sequence and its use in the prevention and/or treatment of cancer. |
申请公布号 |
AU2015254535(A1) |
申请公布日期 |
2016.12.01 |
申请号 |
AU20150254535 |
申请日期 |
2015.04.30 |
申请人 |
Institut Catala D'oncologia (ico);Fundacio Institut D'Investigacio Biomedicia De Bellvitge (Idibell) |
发明人 |
Alemany Bonastre, Ramon;Rojas Exposito, Luis Alfonso |
分类号 |
C12N7/00;C07K14/075 |
主分类号 |
C12N7/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|