FLUORIERUNGSVERFAHREN

摘要

PCT No. PCT/GB94/02732 Sec. 371 Date Oct. 25, 1996 Sec. 102(e) Date Oct. 25, 1996 PCT Filed Dec. 12, 1994 PCT Pub. No. WO95/16649 PCT Pub. Date Jun. 22, 1995According to the present invention there is provided a process for the selective introduction of one or more fluorine atoms into a disubstituted aromatic compound in an acid medium with fluorine gas characterized in that the acid medium has a dielectric constant of at least 20 and a pH of less than 3. The present process provides a cost effective means of selectively introducing one or more fluorine atoms into an aromatic compound in good overall yield.