发明名称 |
SYSTEMS AND METHODS FOR REGULATION OF ONE OR MORE EPIDERMAL OR DERMOEPIDERMAL PROTEINS |
摘要 |
The disclosed embodiments provide skin stimulating devices and methods that address the aging effects of skin at a protein level. Particularly, cyclical mechanical strain is used to regulate specific proteins within the skin, so as to produce specific effects. As a non-limiting example, the disclosed embodiments can be used to increase the production of certain proteins (e.g., hyaluronan synthase 3 (HAS3); fibronectin; tropoelastin; procoll1; integrin, etc.) in the skin, which results in anti-aging effects by increasing epidermal cohesion. |
申请公布号 |
US2016184177(A1) |
申请公布日期 |
2016.06.30 |
申请号 |
US201414588255 |
申请日期 |
2014.12.31 |
申请人 |
L'OREAL |
发明人 |
Caberlotto Elisa;Miller Zane Bowman Allen;Ruiz Laetitia |
分类号 |
A61H15/00 |
主分类号 |
A61H15/00 |
代理机构 |
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代理人 |
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主权项 |
1. A method for modulating one or more cutaneous proteins, the method comprising:
applying a mechanical strain to a portion of skin of a character and for a duration sufficient to affect upregulation of one or more epidermis-associated proteins or dermoepidermal-junction-associated proteins without substantially affecting upregulation of one or more or dermis-associated proteins in the portion of skin. wherein applying the mechanical strain to a portion of skin includes applying a cyclical mechanical strain having a peak cyclic or oscillation frequency ranging from about 100 hertz to about 140 hertz for a duration sufficient to affect upregulation of one or more epidermis-associated proteins or dermoepidermal-junction-associated proteins without substantially affecting upregulation of one or more or dermis-associated proteins in the portion of skin. |
地址 |
Paris FR |