发明名称 |
Method For Creating Endometriotic Cells And Endometriosis Model Animal |
摘要 |
Provided is a method of producing a cell having properties of endometriosis (hereinafter referred to as “endometriotic-like cell”) from a human mesenchymal stem cell. Also provided are a method of producing an animal model exhibiting human endometriosis, the method including transplanting the cell to an animal, and an animal model of endometriosis. The method of producing an endometriotic-like cell comprises a step of culturing a human mesenchymal stem cell induced to differentiate by allowing a differentiation inducing agent to act on the cell, through use of a low-carbon-source culture medium free of a differentiation inducing agent, in a culture vessel coated with extracellular matrix. |
申请公布号 |
US2016192626(A1) |
申请公布日期 |
2016.07.07 |
申请号 |
US201414916574 |
申请日期 |
2014.08.27 |
申请人 |
KYOTO UNIVERSITY ;ASTELLAS PHARMA INC. |
发明人 |
KAJITANI Takashi |
分类号 |
A01K67/027;C12N5/071 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
1. A method of producing an endometriotic-like cell, the method comprising a step of culturing a human mesenchymal stem cell induced to differentiate by allowing a differentiation inducing agent to act on the cell, through use of a low-carbon-source culture medium free of a differentiation induction agent, in a culture vessel coated with extracellular matrix. |
地址 |
Kyoto JP |