发明名称 A METHOD OF INHIBITING TAU PHOSPHORYLATION
摘要 A method of inhibiting phosphorylation of the tau protein and/or a TLR4-mediated immune response is disclosed. The method contemplates administering to cells in recognized need thereof such as cells of the central nervous system an effective amount of a of a compound or a pharmaceutically acceptable salt thereof that binds to a pentapeptide of filamin A (FLNA) of SEQ ID NO: 1, and contains at least four of the six pharmacophores of FIGS. 35-40.
申请公布号 EP2882428(A4) 申请公布日期 2016.09.14
申请号 EP20130816713 申请日期 2013.07.11
申请人 PAIN THERAPEUTICS, INC. 发明人 WANG, HOAU-YAN;BURNS BARBIER, LINDSAY
分类号 A61K31/04;A61K31/438;A61K31/5375;A61K38/08 主分类号 A61K31/04
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