发明名称 derivados de peptídeo e uso dos mesmos como vetores para moléculas na forma de conjugados
摘要 The invention relates to peptide derivatives (peptides and pseudo-peptides) and use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides and prodrug conjugates of the invention can be used to vectorize molecules of pharmaceutical or diagnostic interest, such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes, and notably to promote their transport across the blood-brain barrier (BBB).
申请公布号 BRPI0919777(A2) 申请公布日期 2016.09.20
申请号 BR2009PI19777 申请日期 2009.10.20
申请人 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;UNIVERSITE DE LA MEDITERRANEE;VECT-HORUS 发明人 MARION DAVID;MICHEL KHRESTCHATISKI;PATRICK VLIEGHE;YVES MOLINO
分类号 A61K38/04;C07K7/08;C07K14/775 主分类号 A61K38/04
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