Biocompatible scaffolds with tissue fragments

摘要

A biocompatible tissue repair implant or scaffold device is provided for use in repairing a variety of tissue injuries, particularly injuries to cartilage, ligaments, tendons, and nerves. The repair procedures may be conducted with implants that contain a biological component that assists in healing or tissue repair. The biocompatible tissue repair implants include a biocompatible scaffold and particles of living tissue, such that the tissue and the scaffold become associated. The particles of living tissue contain one or more viable cells that can migrate from the tissue and populate the scaffold.

主权项

1. A biocompatible tissue implant, comprising:
a first bioimplantable scaffold; and a plurality of cartilage tissue fragments distributed on the surface of the first scaffold, the tissue fragments having viable cells, the viable cells being capable of migrating out of the tissue fragments; wherein the cartilage tissue fragments have a size in the range of about 0.1 mm3 to about 3 mm3.