发明名称 |
Use of flavone compound for prevention or treatment of obesity |
摘要 |
The present invention relates to a pharmaceutical composition containing flavone compound as an active ingredient for treating obesity, and more specifically to a pharmaceutical composition for preventing or treating obesity and a dietary composition for preventing or reducing obesity containing 5,7-dimethoxyflavone or 5,7,4′-trimethoxyflavone. The compound according to the present invention inhibits adipogenesis, and reduces expression of the key transcription factors (SREBP1c and C/EBP) related to lipogenesis and of enzyme proteins (FAS and ACC) related to adipogenesis, and thus is effective in preventing or treating obesity. |
申请公布号 |
US9511048(B2) |
申请公布日期 |
2016.12.06 |
申请号 |
US201514541389 |
申请日期 |
2015.03.04 |
申请人 |
Industry-Academic Cooperation Foundation, Yonsei University |
发明人 |
Hwang Jae-Kwan;Kim Myung Suk;Oh Ga Hui |
分类号 |
A61K31/353;A61K31/352 |
主分类号 |
A61K31/353 |
代理机构 |
H.C. Park & Associates, PLC |
代理人 |
H.C. Park & Associates, PLC |
主权项 |
1. A method for treating obesity, the method comprising administering an effective amount of a compound represented by Formula 1 or a salt thereof to a subject in need of obesity treatment wherein each of R1, R2, and R3 consists of hydrogen or a methoxy croup. |
地址 |
Seoul KR |