发明名称 Use of flavone compound for prevention or treatment of obesity
摘要 The present invention relates to a pharmaceutical composition containing flavone compound as an active ingredient for treating obesity, and more specifically to a pharmaceutical composition for preventing or treating obesity and a dietary composition for preventing or reducing obesity containing 5,7-dimethoxyflavone or 5,7,4′-trimethoxyflavone. The compound according to the present invention inhibits adipogenesis, and reduces expression of the key transcription factors (SREBP1c and C/EBP) related to lipogenesis and of enzyme proteins (FAS and ACC) related to adipogenesis, and thus is effective in preventing or treating obesity.
申请公布号 US9511048(B2) 申请公布日期 2016.12.06
申请号 US201514541389 申请日期 2015.03.04
申请人 Industry-Academic Cooperation Foundation, Yonsei University 发明人 Hwang Jae-Kwan;Kim Myung Suk;Oh Ga Hui
分类号 A61K31/353;A61K31/352 主分类号 A61K31/353
代理机构 H.C. Park & Associates, PLC 代理人 H.C. Park & Associates, PLC
主权项 1. A method for treating obesity, the method comprising administering an effective amount of a compound represented by Formula 1 or a salt thereof to a subject in need of obesity treatment wherein each of R1, R2, and R3 consists of hydrogen or a methoxy croup.
地址 Seoul KR