In vitro test for diagnosing enterovirus, useful e.g. for predicting onset of chronic diseases such as diabetes mellitus type I, is based on immunological detection of facilitating antibodies that increase viral infection

摘要

In vivo diagnostic test for enterovirus (EV), based on an antigen (Ag)-antibody reaction, uses Ag, or their epitopes, that do not induce neutralizing antiviral antibodies but rather 'facilitating' antibodies (fAb) that increase viral infection. An Independent claim is also included for a kit for the new test comprising Ag or fAb; reagents for preparing a reaction medium and reagents for detecting the complex formed.