| 发明名称 |
Processo para síntese assimétrica do composto quiral e do composto n-[4-metoxibenzil]-6cloro-2-[r-ciclopropiletinil-hidroxi-trifluorometil-metil anilina quiral e composto |
| 摘要 |
<p>An improved synthesis of a highly potent HIV reverse transcription inhibitor is disclosed, involving an acetylide and a trifluoromethyl ketone which produces a chiral product in the presence of a chiral amino alcohol.</p> |
| 申请公布号 |
BR9608839(A) |
申请公布日期 |
1999.06.08 |
| 申请号 |
BR19969608839 |
申请日期 |
1996.05.21 |
| 申请人 |
MERCK & CO, INC. |
发明人 |
ANDREW S. THOMPSON;EDWARD G. CORLEY;EDWARD J. J. GRABOWSKI;NOBUYOSHI YASUDA |
| 分类号 |
C07B53/00;C07C213/00;C07C215/68;C07C215/70;C07C217/58;C07D265/18;(IPC1-7):C07C213/00 |
主分类号 |
C07B53/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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