NEW 4-ARYLPIPERAZINES AND 4-ARYLPIPERIDINES, PHARMACEUTICAL COMPOSITION AND METHOD OF INHIBITION OF DOPAMINE-2-RECEPTORS

摘要

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to 4-arylpiperazines and 4-arylpiperidines of the formula (I) where A is N or CH; W is C, SO; R1, R - H or C1-4-alkyl; n = 0-4; R3, R - H, alkyl, OH or taken in common as oxygen present carbonyl-group; R - H, C1-8-alkyl, C1-8-alkoxy-, nitro-, amino-, C1-8-acylamino-group; R - H; R is O, S if W is C; R is O if W is SO (other values see p. 1 of the invention claim) that show inhibitory activity with respect to dopamine-2-receptors. EFFECT: new compounds indicated above, inhibitors of receptors. 35 cl, 8 tbl, 113 ex