| 摘要 |
<p>The invention relates to amide and urea derivatives of formula (I): R1-(CH2)n-(Y)q-(Z)r-CO-NH-R2, wherein R1, n, Y, q, Z, r and R¿2? have the meanings indicated in claim 1. Said derivatives are potent 5-HT1B/1D antagonists and 5-HT-reuptake inhibitors and are useful for the treatment and the prophylaxis of anxiety conditions, depressions, schizophrenia, obsessive ideas, tardive dyskinesias, impairment of the learning faculty, age-related memory disorders, for positively influencing obsessive-compulsive disorders (OCD), and in treating and controlling the consequences of cerebral infarctions such as strokes and cerebral ischemias.</p> |
