| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide an adsorbing material for an immunosuppressive substance capable of being spread generally, efficiently and selectively adsorbing the immunosuppressive substance such as TGFβ, immunosuppressive acidic protein, PGE2 or the like directly from body fluids, having no problem from an aspect of health and safety, and capable of being extracorporeally circulated to be made use of in the treatment of cancer. <P>SOLUTION: The adsorbing material for the immunosuppressive substance is obtained by binding amine residues to a water insoluble carrier and sterilizing the amine residue-bound carrier by steam. The column for extracorporeal circulation is packed with this adsorbing material. Further, the adsorbing material for the immunosuppressive substance is an adsorbent obtained by immobilizing the amine residue on the water insoluble carrier and does not lose activity even if it is sterilized with steam. By this constitution, the immunosuppressive substance is adsorbed and removed safely and efficiently and is useful for the treatment of a patient suffering from cancer. <P>COPYRIGHT: (C)2004,JPO&NCIPI |
