| 发明名称 |
PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES |
| 摘要 |
Conjugates of specific PBD dimers with an antibody that binds to CD22, the antibody comprising a VH domain having the sequence according to SEQ ID NO. 1. |
| 申请公布号 |
US2016250346(A1) |
申请公布日期 |
2016.09.01 |
| 申请号 |
US201415028591 |
申请日期 |
2014.10.10 |
| 申请人 |
MEDIMMUNE LIMITED ;ADC THERAPEUTICS SA |
发明人 |
Howard Philip Wilson;Van Berkel Patricius Hendrikus Cornelis |
| 分类号 |
A61K47/48;A61K31/5517;A61K45/06 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A conjugate of formulawherein:
Ab is an antibody that binds to CD22, the antibody comprising a VH domain having the sequence according to SEQ ID NO. 1. |
| 地址 |
CAMBRIDGE GB |
