发明名称 |
Stable Aqueous Formulations of Adalimumab |
摘要 |
The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these compositions, methods of administration, and kits containing same. |
申请公布号 |
US2016256545(A1) |
申请公布日期 |
2016.09.08 |
申请号 |
US201615155832 |
申请日期 |
2016.05.16 |
申请人 |
Coherus Biosciences, Inc. |
发明人 |
Manning Mark;Payne Robert W. |
分类号 |
A61K39/395;C07K16/24 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
1. A buffered aqueous pharmaceutical composition comprising:
(i) adalimumab; (ii) a buffer consisting solely of histidine; and (iii) a polyol; wherein the composition does not contain surfactant. |
地址 |
Redwood City CA US |