发明名称 Stable Aqueous Formulations of Adalimumab
摘要 The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these compositions, methods of administration, and kits containing same.
申请公布号 US2016256545(A1) 申请公布日期 2016.09.08
申请号 US201615155832 申请日期 2016.05.16
申请人 Coherus Biosciences, Inc. 发明人 Manning Mark;Payne Robert W.
分类号 A61K39/395;C07K16/24 主分类号 A61K39/395
代理机构 代理人
主权项 1. A buffered aqueous pharmaceutical composition comprising: (i) adalimumab; (ii) a buffer consisting solely of histidine; and (iii) a polyol; wherein the composition does not contain surfactant.
地址 Redwood City CA US