| 发明名称 |
POLYCLONAL GAMMA DELTA T CELLS FOR IMMUNOTHERAPY |
| 摘要 |
Provided herein is a method of expanding clinically-relevant quantities of polyclonal γδ T cells that have anti-tumor, anti-viral, and anti-bacterial reactivity. Polyclonal γδ T cells can target a variety of tumors, including solid tumors as well as other conditions, such as viral and bacterial infections. |
| 申请公布号 |
US2016256487(A1) |
申请公布日期 |
2016.09.08 |
| 申请号 |
US201415031610 |
申请日期 |
2014.10.24 |
| 申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
COOPER Laurence J.N.;DENIGER Drew C. |
| 分类号 |
A61K35/17;C12N5/0783 |
主分类号 |
A61K35/17 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A cell composition comprising at least about 109 purified γδ T cells, wherein the γδ T cells:
(a) are of the Vδ1, Vδ2, and Vδ1negVδ2neg TCR subsets; (b) have essentially identical genetic material; and (c) do not contain a chimeric antigen receptor. |
| 地址 |
Austin TX US |
